An NYPD EMT, Cassie Web (Dakota Johnson), has a lonesome existence, but she’s more than happy with the way things are while her partner Ben forces her out of her shell and into socializing. A life and death experience brings out a new power laying dormant within her brought on by her mother’s time in the Peruvian Amazon. As her mother lay dying during child birth, locals save Cassie’s life with the help of a rare spider that supposedly offers supernatural powers. Double crossed by her supposed protection Ezekiel Sims (Tahar Rahim), she clung to life just long enough for the birth of her daughter.